Genetic Manipulation of Leishmania donovani to Explore the Involvement of Argininosuccinate Synthase in Oxidative Stress Management.
Reactive oxygen and nitrogen species (ROS Facial Care and RNS) produced by the phagocytic cells are the most common arsenals used to kill the intracellular pathogens.However, Leishmania, an intracellular pathogen, has evolved mechanisms to survive by counterbalancing the toxic oxygen metabolites produced during infection.Polyamines, the major contr